Eric Dane, Grey's Anatomy star, loses ALS battle at 53

A decades-long acting run has been cut short as ALS claimed Eric Dane at 53, leaving behind a grieving family and a wave of tributes.

Eric Dane dies at 53

• Eric Dane died Thursday afternoon after battling ALS.
• His family said he was surrounded by Rebecca Gayheart and daughters, Billie and Georgia.
• Amyotrophic lateral sclerosis attacks nerve cells and causes paralysis.
• Dane had been speaking publicly to raise awareness about the disease.

Signature roles on screen

• Grey’s Anatomy fans knew him as Dr. Mark Sloan.
• Euphoria viewers saw him portray Cal Jacobs.
• His film credits included Marley and Me and Valentine’s Day.
• Charmed and The Last Ship were also part of his resume.

Tributes from colleagues

• Sam Levinson called him a gifted actor and friend.
• Kim Raver praised his humor and lively presence.
• Co-stars highlighted his dedication to the craft.
• Many remembered his sharp comedic timing and warmth.

Career and legacy

• Dane’s career stretched over three decades in Hollywood.
• Versatility defined his performances across genres.
• The family described his children as the center of his world.
• He leaves behind a lasting mark on television and film.